Although NAATs are well-known for their accuracy and sensitivity in detecting most STDs, it is also subject to certain inconsistencies, especially in the case of herpes infections. In Herpes, outbreaks often result in a relative increase in the patient’s viral load – leading to a timeline that usually has specific peaks at certain intervals instead of a consistent rise in viral load throughout. As such, sensitive tests such as NAATs are still unable to accurately diagnose herpes conditions, especially in cases where the patient has recently become asymptomatic and is currently between outbreaks. Other tests such as culture testing and type-specific virologic tests are often employed instead as a confirmatory diagnosis for the patient’s condition.
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