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STD Testing in South Dakota: Free, Same-Day & Confidential

Across South Dakota's 863 cities and towns, testing options vary. Compare confidential, low-cost, and free clinics, labs, at-home kits, and costs, with statewide STI rates alongside.

Find a lab
  • Clinics, labs & at-home kits compared
  • Free & low-cost options included
  • Backed by CDC, CMS & Census data
  • Editorially reviewed

Available testing centers

STD testing in South Dakota

99 public & community clinics serve South Dakota. Below are 13 testing centers from South Dakota's largest cities. Open any city for its full local list.

How to read these listings

Listings tagged Community health center are federally funded health centers and rural clinics that treat everyone regardless of insurance or ability to pay: required to bill on a sliding fee scale and provide confidential care, and in many states minors may consent to their own STI testing. A Title X tag flags centers funded for confidential family-planning services; confirm current participation when you call.

Source: CMS FQHC & Rural Health Clinic enrollment files (data.cms.gov), refreshed quarterly. Title X status reflects the latest OPA grantee list.

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Review sources

  • EasySTD125
Rated 4.9 out of 5 from 125 reviews

Address
713 Omaha Street Rapid City, SD
Opening hours
  • Monday 7:00 AM – 4:00 PM
  • Tuesday 7:00 AM – 4:00 PM
  • Wednesday 7:00 AM – 4:00 PM
  • Thursday 7:00 AM – 4:00 PM
  • Friday 7:00 AM – 4:00 PM
  • Saturday Closed
  • Sunday Closed
  • Chlamydia
  • Gonorrhea
  • Syphilis
  • Herpes
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Rapid HIV
  • Conventional HIV
See tests & prices

Today's offer: $10 off any test panel, applied automatically at checkout.

Community health center Sioux Falls, SD

Falls Community Health

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Review sources

  • EasySTD87
Rated 4.2 out of 5 from 87 reviews

A free or low-cost STD-testing option in Sioux Falls, SD, run as a Federally Qualified Health Center with sliding-scale fees.

Tests & treats Ryan White HIV care Sliding-scale PrEP
Address
521 North Main Avenue, Suite 101 Sioux Falls, SD 57104
Booking
Appointment required
Opening hours
  • Monday 7:30 AM – 5:00 PM
  • Tuesday 7:30 AM – 5:00 PM
  • Wednesday 9:00 AM – 5:00 PM
  • Thursday 7:30 AM – 5:00 PM
  • Friday 7:30 AM – 5:00 PM
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Sioux Falls, SD
Rapid City, SD

South Dakota Department Of Health

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Review sources

  • EasySTD152
Rated 4.4 out of 5 from 152 reviews

A free or low-cost STD-testing option in Rapid City, SD.

Tests & treats
Address
221 Mall Drive, Suite 102 Rapid City, SD 57701
Booking
Appointment required
Website
All testing centers in Rapid City, SD
Community health center Aberdeen, SD

Horizon Health Care

?

Review sources

  • EasySTD230
Rated 4.3 out of 5 from 230 reviews

A public STD-testing option in Aberdeen, SD, run as a Federally Qualified Health Center with sliding-scale fees.

Tests & treats Sliding-scale
Address
506 South Wilson Street, Aberdeen, SD 57401
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 5:00 PM
  • Tuesday 8:00 AM – 5:00 PM
  • Wednesday 8:00 AM – 5:30 PM
  • Thursday 8:00 AM – 5:00 PM
  • Friday 8:00 AM – 5:00 PM
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Aberdeen, SD
Community health center Brookings, SD

Access Health - Brookings

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Review sources

  • EasySTD238
Rated 4.4 out of 5 from 238 reviews

A safety-net clinic in Brookings, SD (Federally Qualified Health Center). Sliding-scale STD testing and care are typical at sites like this, call ahead to confirm the exact panel and pricing.

Sliding-scale
Address
400 22nd Avenue
Website
All testing centers in Brookings, SD
Watertown, SD

Sanford Health

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Review sources

  • EasySTD159
Rated 4.2 out of 5 from 159 reviews

A public STD-testing option in Watertown, SD.

Tests & treats Sliding-scale
Address
703 South Brodway, Watertown, SD 57201
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 5:00 PM
  • Tuesday 8:00 AM – 5:00 PM
  • Wednesday 8:00 AM – 5:00 PM
  • Thursday 8:00 AM – 5:00 PM
  • Friday 8:00 AM – 12:00 PM
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Watertown, SD
Community health center Mitchell, SD

Access Health - Mitchell

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Review sources

  • EasySTD234
Rated 4.5 out of 5 from 234 reviews

A safety-net clinic in Mitchell, SD (Federally Qualified Health Center). Sliding-scale STD testing and care are typical at sites like this, call ahead to confirm the exact panel and pricing.

Sliding-scale
Address
1900 Grassland Drive
Website
All testing centers in Mitchell, SD
Yankton, SD

Yankton Medical Clinic

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Review sources

  • EasySTD93
Rated 4.2 out of 5 from 93 reviews

A public STD-testing option in Yankton, SD.

Tests & treats PrEP DoxyPEP
Address
1104 West 8th Street, Yankton, SD 57078
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 5:30 PM
  • Tuesday 8:00 AM – 5:30 PM
  • Wednesday 8:00 AM – 5:30 PM
  • Thursday 8:00 AM – 5:30 PM
  • Friday 8:00 AM – 5:30 PM
  • Saturday 8:30 AM – 12:00 PM
  • Sunday Closed
Website
All testing centers in Yankton, SD
Pierre, SD

South Dakota Urban Indian Health

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Review sources

  • EasySTD143
Rated 4.5 out of 5 from 143 reviews

A public STD-testing option in Pierre, SD.

Tests & treats Sliding-scale PrEP
Address
339 South Pierre Street, Pierre, SD 57501
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 5:00 PM
  • Tuesday 8:00 AM – 5:00 PM
  • Wednesday 8:00 AM – 5:00 PM
  • Thursday 8:00 AM – 5:00 PM
  • Friday 8:00 AM – 12:00 PM
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Pierre, SD
Spearfish, SD

Monument Health

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Review sources

  • EasySTD75
Rated 4.4 out of 5 from 75 reviews

A public STD-testing option in Spearfish, SD.

Tests & treats Sliding-scale
Address
930 North 10 Street, Spearfish, SD 57783
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 5:00 PM
  • Tuesday 8:00 AM – 5:00 PM
  • Wednesday 8:00 AM – 5:00 PM
  • Thursday 8:00 AM – 5:00 PM
  • Friday Closed
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Spearfish, SD
Pine Ridge, SD

Indian Health Service

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Review sources

  • EasySTD60
Rated 4.7 out of 5 from 60 reviews

A free or low-cost STD-testing option in Pine Ridge, SD.

Tests & treats Sliding-scale
Address
East Hwy 18, Pine Ridge, SD 57770
Booking
Appointment required
Opening hours
  • Monday 8:00 AM – 4:30 PM
  • Tuesday 8:00 AM – 4:30 PM
  • Wednesday 8:00 AM – 4:30 PM
  • Thursday 8:00 AM – 4:30 PM
  • Friday 8:00 AM – 4:30 PM
  • Saturday Closed
  • Sunday Closed
Website
All testing centers in Pine Ridge, SD
Community health center Chamberlain, SD

Access Health - Chamberlain

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Review sources

  • EasySTD30
Rated 4.5 out of 5 from 30 reviews

A safety-net clinic in Chamberlain, SD (Federally Qualified Health Center). Sliding-scale STD testing and care are typical at sites like this, call ahead to confirm the exact panel and pricing.

Sliding-scale
Address
101 South Front Street
Website
All testing centers in Chamberlain, SD
Community health center North Eagle Butte, SD

Horizon Health - Eagle Butte

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Review sources

  • EasySTD81
Rated 4.7 out of 5 from 81 reviews

A safety-net clinic in North Eagle Butte, SD (Federally Qualified Health Center). Sliding-scale STD testing and care are typical at sites like this, call ahead to confirm the exact panel and pricing.

Sliding-scale
Address
24337 US Highway 212
Website
All testing centers in North Eagle Butte, SD

Free tool · not a clinic

When can I test? Exposure-window calculator

Testing too soon can miss an infection. Enter the date of possible exposure to see the earliest a test can reliably detect each STI.

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What matters most to you?

What will it cost? Estimate your STD test

Typical out-of-pocket ranges by option, actual cost depends on which tests you need.

  • Public / community clinic

    Free HIV testing is common

    $0–$25
  • Private lab (self-pay)

    Never billed to insurance

    $24–$200
  • At-home kit

    Mailed to your door, private

    From $49
  • Doctor / urgent care

    Often $0 preventive with insurance

    $0–$50 copay

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Test from home

At-home STD testing in South Dakota

if you'd rather skip the trip, an at-home kit ships to South Dakota, you collect the sample privately, and mail it back to a CLIA-certified lab. Results come online in days, with a clinician available if anything is positive. Same labs as a clinic, no waiting room, and you can read how accurate at-home STD tests are before you order.

Want a free option first? The CDC-supported TakeMeHome program mails free at-home HIV self-test kits, and, in many areas, free STI kits, to your door, with no insurance or payment needed. The paid kits below add broader panels and faster turnaround.

  • In-home collection

    Quest Diagnostics

    Quest Diagnostics

    $79 & up

    Panel:
    8-infection panel incl. chlamydia, gonorrhea, HIV, syphilis, hepatitis & herpes: single tests too
    Sample:
    Quest Mobile: a phlebotomist collects your sample at home
    Results:
    1–3 days, online: physician-reviewed
    • In-home sample collection
    • Nationwide Quest lab network
    • Physician-reviewed results
    • FSA/HSA eligible
  • Best value: single tests

    Everlywell

    Everlywell

    $49 & up

    Panel:
    Chlamydia & gonorrhea, up to a 6-test panel adding HIV, syphilis, trichomoniasis & hep C
    Sample:
    Finger-prick + swab
    Results:
    Days, online
    • Telehealth visit if positive
    • CLIA-certified labs
    • HSA/FSA eligible
    • Subscription savings
  • Best range: couples & full panels

    myLAB Box

    myLAB Box

    $79 & up

    Panel:
    Up to 14 infections, incl. HIV, syphilis, chlamydia, gonorrhea, hepatitis & herpes
    Sample:
    Self-collect: swab, urine, finger-prick
    Results:
    2–5 days, online
    • Free phone consult if positive
    • CLIA-certified labs
    • Couples & subscription options
    • Discreet packaging

Every kit uses CLIA-certified labs. At-home testing is for screening; a reactive result should be confirmed and treated by a clinician. Prices and panels shown are illustrative and change often, confirm current details on the provider's site.

Also in the area

CLIA-certified labs across South Dakota

Beyond the public testing sites above, these federally certified (CLIA) labs operate across South Dakota, each lab's town is shown on its card below. Many test through a doctor's order or by appointment rather than walk-in, so call ahead to confirm STD/STI testing and availability before visiting.

  • Sanford Laboratories - 49th And Oxbow

    3401 West 49th

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D0675751

    • Full STD panel
  • Sanford Laboratories Harrisburg

    111 North Cliff Avenue

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D2264390

    • Full STD panel
  • Sanford Laboratories - Mitchell

    2100 Highland Way Suite K

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D1066801

    • Full STD panel
  • Sanford Laboratories - Pierre

    521 East Sioux Avenue

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D1065686

    • Full STD panel
  • Sanford Laboratories - Hartford

    905 North Oaks Avenue

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D0934475

    • Full STD panel
  • Wanblee Health Ctr - Pine Ridge

    Box 290

    Certificate of AccreditationAccredited · Joint CommissionCLIA #43D0876870

    • Full STD panel

Source: CMS CLIA registry (Provider of Services), Q1 2026. Federal public records, filtered to active labs certified for moderate-to-high-complexity testing, the level chlamydia/gonorrhea NAAT and syphilis serology require, across South Dakota. Any star rating is the CMS Hospital Compare overall rating where the lab is a rated hospital. Inclusion is not an endorsement and doesn't confirm a facility offers STD testing, always call to verify.

Prevention & treatment

PrEP, prevention & online treatment

Testing is one step. For residents of South Dakota, telehealth covers the rest: HIV-prevention medication (PrEP) and DoxyPEP to lower future risk, and discreet online treatment if a result comes back positive. All prescribed by licensed U.S. clinicians.

Pricing varies by insurance and changes often, confirm on the provider's site. These services are not a substitute for emergency care.

STD stats & rates

STDs & HIV in South Dakota: the statewide picture

How reported STI rates across South Dakota compare with the Midwest region and the United States, using the most recent CDC surveillance data. Data for all 66 counties feeds the county and city pages linked below. About 9.3% of South Dakota adults are uninsured, a key reason the free and low-cost testing options below matter.

An estimated ~28% of South Dakota residents are aged 15–34 (ACS): the age group with the highest reported chlamydia and gonorrhea rates nationally, which is why testing access across the state matters.

#15 of 51 U.S. states & DC for reported chlamydia

  • Chlamydia #15 of 51
  • Gonorrhea #5 of 51
  • Syphilis #1 of 51
  • Congenital syphilis #1 of 51
  • HIV #33 of 51

Reported STD rates per 100,000, South Dakota vs Midwest vs U.S.

South Dakota Midwest U.S. ▲▼ = South Dakota vs the U.S. average
Infection South Dakota Midwest United States
Chlamydia
531.6 4,887 cases ▲ 8%
469.4 492.2
Gonorrhea
253.3 2,329 cases ▲ 41%
161.6 179.5
Syphilis (P&S)
73.4 675 cases ▲ 365%
12.9 15.8
Syphilis (early)
76.8 706 cases ▲ 380%
10.1 16
Syphilis (late/unknown)
72.9 670 cases ▲ 147%
19.3 29.5

Rates per 100,000 population, latest year. Source: CDC NCHHSTP AtlasPlus (all-ages basis). Bars are scaled to the highest rate shown; the badge is each South Dakota rate versus the U.S. average.

Reported STD rates in South Dakota over time (per 100,000)

Chlamydia ▼6% vs 2022
ChlamydiaGonorrheaSyphilis (P&S)
03006002020202120222023

Between 2020 and 2023 in South Dakota, chlamydia has risen from 456.1 to 531.6 per 100,000 (17%), gonorrhea has fallen from 273.4 to 253.3 per 100,000 (7%), and P&S syphilis has risen from 7.4 to 73.4 per 100,000 (892%).

The 2020 dip reflects reduced pandemic-era screening, not lower transmission. Source: CDC NCHHSTP AtlasPlus.

Community health context

What shapes testing access in South Dakota

Adults uninsured
9.3%
Primary-care shortage counties
53 of 66
Public & community clinics
99
Pharmacies statewide
287

Social Vulnerability Index · South Dakota's counties average the 37th percentile nationally

Lower insurance coverage and a thin clinic-to-population ratio raise the value of free public clinics and confidential at-home testing across South Dakota (pop. 919,318). Sources: U.S. Census ACS (uninsured), HRSA & CDC NPIN (clinics), NPPES & OpenStreetMap (pharmacies), CDC/ATSDR SVI.

Statewide HIV snapshot

HIV in South Dakota (2023)

New diagnoses
6.8 / 100k
People living with HIV
814
On PrEP (coverage)
29.9%
Virally suppressed
60.4%

South Dakota HIV care continuum (2023)

South Dakota reports 6.8 new HIV diagnoses per 100,000, below the U.S. rate of 13.7. The rate has risen31% since 2020. Among South Dakota residents living with HIV, 82.5% know their status · 86.5% are linked to care · 89.4% are in care · 60.4% are virally suppressed. On prevention, 29.9% of those who could benefit from PrEP are taking it (below the 31.3% national average). Early, routine testing is what moves these numbers: it is the entry point to PrEP, treatment, and viral suppression.

Source: CDC NCHHSTP AtlasPlus. The CDC recommends everyone aged 13–64 test for HIV at least once, every clinic and lab listed above offers HIV testing.

Also screened

Viral hepatitis in South Dakota

Comprehensive panels also screen for hepatitis B and C, both sexually transmissible. Per 100,000, South Dakota vs U.S.

Hepatitis A (acute)
0.4U.S. 0.5
Hepatitis B (acute)
0.3U.S. 0.7
Hepatitis C (acute)
1.1U.S. 1.5

Congenital syphilis in South Dakota

Pregnant or planning to be?

Congenital syphilis, passed from parent to baby in pregnancy, is the fastest-rising STI in the country. South Dakota reported 54 cases in 2023, up from 4 in 2020. Nationally, cases climbed from 2,163 (2020) to 3,882 (2023). It is almost entirely preventable with a syphilis test at the first prenatal visit.

Source: CDC NCHHSTP AtlasPlus, 2023.

How South Dakota's STD rates compare

South Dakota reported a chlamydia rate of 531.6 per 100,000 in its most recent surveillance year, 8% above the U.S. average of 492.2, and above the Midwest regional rate of 469.4. Gonorrhea ran 253.3 per 100,000, and primary-and-secondary syphilis 73.4.

Among the 50 states and DC, South Dakota ranks #15 of 51 for chlamydia. Statewide chlamydia has risen 17% since 2020. The 2020 dip in the trend reflects reduced pandemic-era screening, not lower transmission, and because most STDs are silent, reported counts understate true spread.

Access and cost across South Dakota

Testing reaches every corner of South Dakota: 99 public and community health clinics test free or on a sliding scale, private walk-in labs return results in 1–2 days, and at-home kits ship to every ZIP code, with the densest options around Sioux Falls, Rapid City, and Aberdeen.

About 9.3% of South Dakota adults are uninsured and 12.6% live below the poverty line, so cost is the most common reason testing gets delayed. Free public-clinic testing, sliding-scale community health centers, and self-pay private labs that never bill insurance keep screening within reach, weigh them on price, privacy, and turnaround using the comparison above.

Who's most at risk, and how often to test

About 28% of South Dakota residents are aged 15–34. The CDC estimates people aged 15–24 account for roughly half of all new STIs nationwide despite being a small share of the population, so screening guidance is age-aware.

Sexually active women under 25, and anyone with new or multiple partners, should test for chlamydia and gonorrhea every year; everyone aged 13–64 should test for HIV at least once; and pregnant residents are screened early in pregnancy. Because most STDs cause no symptoms, testing on the CDC's schedule, not only when something feels wrong, is the reliable way to catch an infection before it spreads.

Prevention, vaccines, and where to get help

Testing is one pillar; prevention is the other. South Dakota county and city health departments distribute free condoms, offer HIV counseling, and provide hepatitis A/B and HPV vaccination that heads off several of the infections screened for here, while PrEP and DoxyPEP sharply cut HIV and bacterial-STI risk.

If a result is positive, treatment is close to home: chlamydia, gonorrhea, syphilis, and trichomoniasis are curable with antibiotics, while HIV and herpes are managed with ongoing care. Public health departments treat on site and most private labs include a clinician consult, start with a free or low-cost South Dakota clinic above, or an at-home kit for private, mail-in screening.

Why it matters

Why STD testing matters

Find a lab near you
  • Reported counts only capture people who got tested: and with South Dakota's rates running above the national average and most STDs causing no symptoms, the true spread is higher still. That gap is exactly why routine screening matters here.
  • Untreated, these infections do lasting damage: chlamydia and gonorrhea scar the reproductive system and cause infertility; syphilis can lead to stillbirth and organ damage; any active STI raises HIV risk. Caught early, almost all are curable or controllable with a single course of treatment.
  • Make it routine, not reactive: test as part of your annual check-up if you're sexually active, every three months with new or multiple partners, and before unprotected sex with a new partner. Since 2015 the CDC has urged insurers to cover annual screening for women under 25 at no cost.
  • Testing protects more than you: a silent infection passes to partners unknowingly. When South Dakota residents test on a schedule, the whole state's transmission drops, knowing your status is the single highest-leverage thing you can do.

Medically Reviewed & Fact-Checked · Updated

Reviewed by EasySTD Editorial Team

Compiled and checked by EasySTD's editorial team against CDC and public-health sources. This is educational information, not a substitute for advice from a licensed clinician. Our editorial guidelines →

11 Sources

Data & references

Local context

About South Dakota

South Dakota's gonorrhea rates are among the highest in the nation. The distances between towns are real, the roads in winter are real, and for most of the state's 66 counties, federally recognized gaps in primary-care availability mean that a routine gonorrhea test isn't as simple as walking into a nearby clinic. Sioux Falls and Rapid City anchor the state's testing infrastructure, but the overwhelming majority of South Dakota's counties fall outside easy reach of those hubs, making geography one of the most honest predictors of whether someone actually gets screened. That access gap lands unevenly.

South Dakota's young adults, a share of the population large enough to represent real transmission risk, are also the group most likely to be uninsured, and the state's uninsured rate means a meaningful portion of people who need testing are weighing cost before they walk in the door. The public and community clinics distributed across the state exist precisely to absorb that pressure, though their reach is tested by how spread out 863 towns across a vast landscape can be. If you're in Sioux Falls, Rapid City, Aberdeen, or Brookings, same-day or next-day options are realistic. If you're not, knowing which clinic serves your area, and whether it offers sliding-scale fees, is the practical first step this page is built to answer.

Free & low-cost testing in all 66 counties · at-home kits ship statewide

Largest metros

Where most South Dakota testing demand concentrates, each has its own local guide.

South Dakota snapshot

Who gets tested in South Dakota

State-level Census (ACS) figures that shape testing demand and access. Median age and income are population-weighted estimates.

Residents
919,318
Median age
37
Median income
$69,475
Below poverty
12.6%
College-educated
32%

Getting there

Major routes serving South Dakota

The interstates and highways that connect South Dakota's testing sites, most clinics and labs sit on or near one of these corridors.

  • SD 34 (East 7th Street)
  • US 14 (East Elm Street)
  • US 212 (4th Street)
  • US 18 (US Highway 18)
  • SD 44 (SD Highway 44)
  • US 281 (US Highway 281)
  • US 12 (US Highway 12)
  • I 90 (Purple Heart Memorial Highway)

Reference

STD testing in South Dakota: screening, costs & privacy

Everything to know before you test in South Dakota: the CDC's screening guidelines, each infection's detection window, per-test reference prices, and your privacy rights under South Dakota law.

Who should test, and whenCDC screening schedule + each infection's detection window

Who should get tested, and how often

Based on current CDC screening recommendations.

Group Tests How often
Everyone aged 13–64 HIV At least once
Sexually active women under 25 Chlamydia, gonorrhea Every year
Women 25+ with new or multiple partners Chlamydia, gonorrhea Every year
Pregnant people HIV, syphilis, hepatitis B & C, chlamydia Early in pregnancy
Gay & bisexual men (MSM) Chlamydia, gonorrhea, syphilis, HIV Every 3–6 months
Anyone who shares injection equipment HIV, hepatitis B & C At least yearly
All adults at least once Hepatitis C At least once

When to test: STD detection windows

Testing too early can return a false negative, confirm timing with a South Dakota-area provider.

Infection Earliest reliable test Sample
Chlamydia 1–2 weeks Urine or swab
Gonorrhea 1–2 weeks Urine or swab
Trichomoniasis 1–4 weeks Urine or swab
HIV (NAT / RNA) 10–33 days Blood
HIV (4th-gen Ag/Ab) 18–45 days Blood
HIV (antibody) 3–12 weeks Blood / oral
Syphilis 3–6 weeks Blood
Hepatitis B 3–6 weeks Blood
Hepatitis C 8–11 weeks Blood
Herpes (HSV) 4–16 weeks (antibody); swab a sore Blood / swab
Browse all STD & STI guides
What each STD test costsMedicare reference prices per lab test, a benchmark before you pay out of pocket

These are the federal Medicare reference prices for processing each lab test. Public clinics and the community health centers serving South Dakota often test free or on a sliding scale; private labs and at-home kits bundle several tests into one fee. Use this as a per-test benchmark before you pay out of pocket, or see the full guide to STD test costs for insurance, free, and at-home options.

Test Reference price CPT / HCPCS
Chlamydia (NAAT) $47.80 87491
Gonorrhea (NAAT) $47.80 87591
Trichomoniasis (NAAT) $47.76 87661
HIV-1/2 antigen/antibody $26.87 87389
HIV-1/2 antibody $22.44 86703
Syphilis (RPR/VDRL) $5.61 86592
Syphilis (treponemal antibody) $17.49 86780
Herpes (HSV NAAT) $47.76 87529
Hepatitis B surface antigen $15.33 87340
Hepatitis C antibody $29.16 86803

Source: Medicare Clinical Laboratory Fee Schedule, CMS, 2025 rates (data.cms.gov). Reference rate for the lab assay only: a clinic visit, sample collection, or a bundled multi-test panel may cost more. Medicaid and most insurers cover STD screening at no out-of-pocket cost.

Confidentiality & consent in South DakotaMinor consent and partner treatment (EPT) under state law, plus how to test privately

Two things that actually depend on South Dakota law: who can consent, and whether partners can be treated without their own visit. Everything else about testing privately is the same nationwide (see below).

Can a minor consent on their own?

In South Dakota, a minor of any age can consent to confidential STI testing and treatment on their own, no parental permission is required.

Can my partner be treated too? (EPT)

Expedited Partner Therapy (EPT) is potentially allowable in South Dakota: it is not expressly authorized, but not prohibited either. Ask your provider whether they will prescribe treatment for a partner without a separate visit.

Keeping a test private works the same in every state. Whether an STD test shows on insurance (the EOB), how to test anonymously, and self-pay options that leave no insurance trail don’t change by location.

Learn more about confidential STD testing in South Dakota

Source: Guttmacher Institute, Minors' Access to STI Services; CDC, Legal Status of Expedited Partner Therapy. General information, not legal advice.

Good to Know

STD testing FAQs in South Dakota

Answers to the questions South Dakota residents ask most before getting tested, from privacy and cost to timing and at-home options.

How does South Dakota rank for STDs in the U.S.?

Among the 50 states and DC, South Dakota ranks #15 of 51 for chlamydia, reporting about 532 cases per 100,000 (8% above the U.S. average). Reported counts understate the true total because most infections are silent, which is why routine screening matters statewide.

Which STDs are rising in South Dakota?

Since 2020, syphilis is up about 892%, chlamydia is up about 17% in South Dakota. Syphilis, including congenital syphilis passed to newborns, is the fastest-growing STI nationally, so prenatal and routine screening are a priority here too.

What is the HIV situation in South Dakota today?

South Dakota reports about 6.8 new HIV diagnoses per 100,000 residents a year, a rate that has risen in recent years. About 60.4% of residents living with HIV are virally suppressed, undetectable means the virus can't be sexually transmitted (U=U). PrEP and free HIV testing are available across the state.

How common is chlamydia in South Dakota versus the U.S.?

South Dakota reported about 532 chlamydia cases per 100,000 (2023), 8% above the U.S. average of 492. It is the most commonly reported STD here, and often silent, so under-25s and anyone with new partners should screen yearly.

Is congenital syphilis a concern in South Dakota?

Congenital syphilis, when syphilis passes from parent to baby in pregnancy, is the fastest-rising STI crisis in the U.S. (about 3,882 U.S. cases in 2023), and it is almost entirely preventable with a simple blood test early in pregnancy. South Dakota recommends syphilis screening at the first prenatal visit, so testing while pregnant, or before, matters here.

Will STD testing show up on my insurance in South Dakota?

If you use health insurance, an Explanation of Benefits (EOB) may be mailed to the policyholder, which could be a parent or spouse. Under HIPAA (45 CFR 164.522) you can ask your insurer in writing to send communications to you confidentially. To leave no insurance trail at all, use a self-pay private lab, an at-home test kit, or a public health clinic, none of these bill your insurance.

Can I get tested anonymously in South Dakota?

Anonymous HIV testing is available at some sites in South Dakota; elsewhere testing is confidential (name-based) but still protected. Public health clinics and at-home kits also let you test without involving insurance or your regular doctor.

Can my partner be treated without their own visit in South Dakota?

Expedited Partner Therapy (EPT) is potentially allowable in South Dakota: it is not expressly authorized, but not prohibited either. Ask your provider whether they will prescribe treatment for a partner without a separate visit.

Where can I get free or low-cost STD testing across South Dakota?

South Dakota's 99 public and community health clinics, county and city health departments, FQHCs, and Title X family-planning sites, test for free or on a sliding scale statewide, which matters where about 9.3% of adults are uninsured. Pick your city below for the specific clinics nearest you.

How much does STD testing cost in South Dakota?

Free or sliding-scale at South Dakota's public clinics and FQHCs (Medicaid accepted); at-home kits run about $50–$150 for a full panel; private walk-in labs charge per test. No one is turned away for inability to pay at public health clinics.

How do I get PrEP for HIV prevention in South Dakota?

PrEP, a daily pill that prevents HIV, is available across South Dakota through health departments, FQHCs, and many primary-care and telehealth providers, often free or low-cost via insurance, Medicaid, or manufacturer assistance programs. Alongside testing and treatment, it's central to the state's HIV response. Any South Dakota clinic can start you, or you can begin through a telehealth service.

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