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STD & STI Conditions, Explained

Symptoms, the testing window, cost and treatment for every STD and STI we cover, in plain language, from chlamydia to HIV.

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Curable with antibiotics

Bacterial STIs

The most common, and the most curable. A short course of antibiotics clears them, but they're frequently silent, which is exactly why testing matters.

  • Most reported Curable

    Chlamydia

    Chlamydia trachomatis

    Chlamydia is the most reported STI in the United States, 1.65 million cases in 2023, and most were invisible.

    Test window 1–2 weeks
  • Curable

    Gonorrhea

    Neisseria gonorrhoeae

    Gonorrhea is the second most reported STI in the United States, and it's in a race against our antibiotics.

    Test window 1–2 weeks
  • Curable

    Syphilis

    Treponema pallidum

    Syphilis moves through stages: a painless sore, a distinctive rash, years of silence, and then, untreated, irreversible damage to the heart, brain, and eyes.

    Test window 3–6 weeks
  • Curable

    Mycoplasma genitalium

    Mycoplasma genitalium: a cell-wall-lacking bacterium, distinct from Mycoplasma hominis, making it intrinsically resistant to all beta-lactam antibiotics

    Mycoplasma genitalium (MG) is an emerging bacterial STI with a catch: the antibiotics most people know don't work on it.

  • Curable

    Nongonococcal urethritis (NGU)

    Urethritis not caused by gonorrhea (multiple causes. Chlamydia trachomatis, Mycoplasma genitalium, and others)

    Nongonococcal urethritis (NGU) is inflammation of the urethra not caused by gonorrhea.

  • Curable

    Chancroid

    Haemophilus ducreyi, a gram-negative bacterium

    Chancroid, caused by the bacterium Haemophilus ducreyi, produces painful genital ulcers and tender, swollen lymph nodes in the groin.

  • Curable

    Lymphogranuloma venereum (LGV)

    Chlamydia trachomatis serovars L1, L2, or L3

    Lymphogranuloma venereum (LGV) is an aggressive form of chlamydia caused by more invasive strains of Chlamydia trachomatis.

  • Curable

    Granuloma Inguinale (Donovanosis)

    Klebsiella granulomatis (formerly Calymmatobacterium granulomatis)

    Granuloma inguinale (donovanosis) is a rare bacterial STI caused by Klebsiella granulomatis.

Manageable & preventable

Viral STIs

Managed with medication and, increasingly, prevented, the HPV vaccine and HIV PrEP. Early testing keeps them in check.

  • Manageable

    HIV/AIDS

    Human immunodeficiency virus (HIV-1/HIV-2)

    HIV is manageable now, but only if you know your status.

  • Manageable

    Genital Herpes

    Herpes simplex virus (HSV-1 and HSV-2)

    Genital herpes is one of the most common, and most misunderstood, STIs in the world.

    Test window 4–16 weeks (antibody); swab a sore
  • Most common

    HPV

    Human Papillomavirus (HPV), a double-stranded DNA virus; 200+ types; ~40 infect the anogenital tract

    HPV (human papillomavirus) is the most common STI in the United States: about 43 million Americans had an active infection in 2018, with an estimated 13 million new infections a year.

  • Manageable

    Genital warts

    Human Papillomavirus (HPV) types 6 and 11: low-risk, non-oncogenic types that never cause cancer

    Genital warts come from low-risk HPV types 6 and 11, not the cancer-causing strains.

  • Curable

    Mpox

    Monkeypox virus (Orthopoxvirus)

    Mpox, caused by the monkeypox virus, spreads mainly through close skin-to-skin contact, including intimate and sexual contact.

Vaccine-preventable

Viral hepatitis

Liver infections spread through sex or blood. Hepatitis A and B are vaccine-preventable; hepatitis C is now curable.

  • Manageable

    Hepatitis B

    Hepatitis B virus (HBV), a DNA virus of the Hepadnaviridae family

    Hepatitis B is a vaccine-preventable liver infection caused by a DNA virus spread through blood, body fluids, sex, and mother-to-child contact at birth.

    Test window 3–6 weeks
  • Curable

    Hepatitis C

    Hepatitis C virus (HCV), an RNA virus of the Flaviviridae family; 6 major genotypes (1a and 1b most common in the U.S.)

    Hepatitis C silently damages the liver for decades, but it's now curable with a short course of pills: an 8–12 week regimen of direct-acting antivirals cures more than 95% of people.

    Test window 8–11 weeks
  • Curable

    Hepatitis A

    Hepatitis A virus (HAV): a non-enveloped, single-stranded RNA virus of the family Picornaviridae

    Hepatitis A is a vaccine-preventable liver infection caused by the hepatitis A virus (HAV).

Treatable infestations

Parasitic & skin infections

Sexually transmissible parasites and skin infections: uncomfortable, but all straightforward to treat.

  • Curable

    Trichomoniasis

    Trichomonas vaginalis

    Trichomoniasis is the most common curable non-viral STI in the United States: a single-celled parasite, present in an estimated 2 million people, and silent in roughly 70% of them.

    Test window 1–4 weeks
  • Curable

    Pubic lice (crabs)

    Pthirus pubis: the pubic or crab louse, a parasitic insect; a distinct species from head lice (Pediculus humanus capitis) with different biology, habitat, and treatment requirements

    Pubic lice ("crabs," named for their hooked, claw-like front legs) are tiny parasitic insects that cling to coarse body hair and spread almost entirely through close sexual contact.

  • Curable

    Scabies

    Sarcoptes scabiei var. hominis, a microscopic parasitic mite (0.3 mm) that burrows into the outermost layer of human skin to live and reproduce

    Scabies is a fully curable skin infestation caused by a microscopic mite that burrows into the top layer of skin, causing an intensely itchy rash that's classically worst at night.

  • Curable

    Molluscum contagiosum

    Molluscum contagiosum virus (MCV), a poxvirus; 4 subtypes; MCV-1 most common overall; MCV-2 most common in sexually transmitted adult cases

    Molluscum contagiosum is a contagious poxvirus skin infection that produces small, dome-shaped bumps with a telltale central dimple.

Symptom overlap

Same symptoms, different infections

Many STIs share the same handful of signs, and the same infection can look different from one person to the next. Most are often symptomless altogether: which is exactly why a test, not a symptom, is the only way to be sure. Use this to orient, then open a guide for the specifics.

common sign not typical A guide, not a diagnosis: symptoms vary widely, overlap, and are frequently absent. For anything you're worried about, open the condition guide or get tested.

Still not sure what you're looking at? Use the guided symptom checker for a personalized starting point, then test to be sure.

Treatment at a glance

How each one is treated

Most STIs are cured with a short course of medicine, and the rest are very manageable. Pick an infection to see the CDC-recommended regimen, the option if you're allergic to penicillin, what's safe in pregnancy, and roughly what it costs, so you know what to ask your provider for.

General information, not a prescription. This runs on your device: nothing is sent or saved.

Which infection?

Four things that hold for almost every STI

Treat partners too

Getting treated while your partner isn't is the top cause of reinfection. Many states allow Expedited Partner Therapy so they can be treated without their own visit.

Wait 7 days

For the curable STIs, don't have sex until 7 days after treatment and until partners are treated, and until symptoms clear.

Retest in 3 months

Reinfection is common, so the CDC recommends re-testing about 3 months after treatment for chlamydia, gonorrhea and trich.

Finish the full course

Take every dose even if you feel better fast. Stopping early can leave infection behind and drive resistance.

Already treated? Get your safe-to-have-sex and retest dates, or read how long treatment takes to work.

Editorial standards and sources

Medically Reviewed & Fact-Checked · Updated

Reviewed by EasySTD Editorial Team

Compiled and checked by EasySTD's editorial team against CDC and public-health sources. This is educational information, not a substitute for advice from a licensed clinician. Our editorial guidelines →

10 Sources

Data & references