Gonorrhea reports in Jefferson County run about 59% lower than the US average. If you're considering STI testing in De Soto, Missouri, whether after a possible exposure or as part of routine care, you'll find clinics where a provider can address your questions and start treatment, while at-home kits let you collect a sample when it suits you and mail it in. Options below.
Available testing centers
9 testing options are listed for De Soto, MO. The nearest, Midwest Medical Practitioners, is about 0.4 miles away. Compare community and public clinics, private labs, and at-home kits below.
Listings tagged Community health center are federally funded health centers and rural clinics that treat everyone regardless of insurance or ability to pay: required to bill on a sliding fee scale and provide confidential care, and in many states minors may consent to their own STI testing. A Title X tag flags centers funded for confidential family-planning services; confirm current participation when you call.
Source: CMS FQHC & Rural Health Clinic enrollment files (data.cms.gov), refreshed quarterly. Title X status reflects the latest OPA grantee list.
A public safety-net rural health clinic in De Soto. Sliding-scale STD testing and care are typical here, call ahead to confirm the exact panel and pricing.
Tests offered
Compass Health Network in Hillsboro runs STI care on a sliding-scale fee structure, accepting Medicaid, Medicare, and private insurance alongside donation-based options. Appointments are required; testing covers gonorrhea, chlamydia, syphilis, rapid and conventional HIV, hepatitis C, and TB, with same-visit treatment for bacterial infections and HPV, hepatitis A, and hepatitis B vaccines available.
Languages
English
Tests offered
Serves
Care services
Prevention services
Fees & payment
Listing verified Feb 2026 · Source: CDC NPIN + HRSA
Jefferson County Health Department in Hillsboro tests for gonorrhea, chlamydia, syphilis, and HIV on a sliding-scale fee structure, with appointments required and same-visit treatment available for bacterial infections. All services provided at no fee.
Jefferson County Health Department carries no charge for any service on its roster: STI testing, STI treatment, vaccines including Mpox and HPV, TB evaluation, and family planning all fall under a structure where the sliding scale bottoms out at nothing. The fee line exists; the balance does not.
As a Title X-designated site, Jefferson County Health Department provides family planning under federal statute, which means services for minors are legally confidential, not at the clinic's discretion but by the terms of the program itself. That statutory protection is built into the funding structure, not added as a policy layer.
Languages
English
Tests offered
Serves
Care services
Prevention services
Fees & payment
Listing verified Apr 2026 · Source: CDC NPIN
Compass Health in Hillsboro charges on a sliding scale tied to income, so cost isn't a barrier regardless of what someone can pay. Federal FQHC status anchors that commitment. STI screening here covers syphilis, gonorrhea, and chlamydia. No appointment needed to get started.
Tests offered
Fees & payment
Compass Health in Festus structures its fees on a sliding scale tied to income, so cost doesn't become a barrier to care. As a federally qualified health center, it offers STI screening (syphilis, gonorrhea, and chlamydia) with no appointment required.
Tests offered
Fees & payment
Free tool · not a clinic
Testing too soon can miss an infection. Enter the date of possible exposure to see the earliest a test can reliably detect each STI.
| Infection | Earliest reliable test | Conclusive after |
|---|---|---|
| Chlamydia | 7 days after exposure | 14 days after exposure |
| Gonorrhea | 7 days after exposure | 14 days after exposure |
| Trichomoniasis | 7 days after exposure | 28 days after exposure |
| HIV (NAT / RNA) | 10 days after exposure | 33 days after exposure |
| HIV (4th-gen Ag/Ab) | 18 days after exposure | 45 days after exposure |
| HIV (antibody) | 21 days after exposure | 84 days after exposure |
| Syphilis | 21 days after exposure | 42 days after exposure |
| Hepatitis B | 21 days after exposure | 42 days after exposure |
| Hepatitis C | 56 days after exposure | 77 days after exposure |
| Herpes (HSV) | 28 days after exposure | 112 days after exposure |
Guidance only, confirm timing with a clinician. A negative result before the conclusive date may need a repeat test.
Typical out-of-pocket ranges by option, actual cost depends on which tests you need.
Public / community clinic
Free HIV testing is common
Private lab (self-pay)
Never billed to insurance
At-home kit
Mailed to your door, private
Doctor / urgent care
Often $0 preventive with insurance
No centers match those filters. Clear the service-type filter or the opening-hours filters to see every center.
Every other option
Beyond the dedicated testing centers above: at-home kits by mail, hospital labs certified for STI testing, local clinicians who can order a panel during a regular visit, pharmacies for self-test kits and prescriptions, and online PrEP & treatment.
Test from home
The nearest testing center is less than a mile away; if you'd rather skip the trip, an at-home kit ships to De Soto, you collect the sample privately, and mail it back to a CLIA-certified lab. Results come online in days, with a clinician available if anything is positive. Same labs as a clinic, no waiting room, and you can read how accurate at-home STD tests are before you order.
Want a free option first? The CDC-supported TakeMeHome (opens in a new tab) program mails free at-home HIV self-test kits, and, in many areas, free STI kits, to your door, with no insurance or payment needed. The paid kits below add broader panels and faster turnaround.
In-home collection
$79 & up
Best range: couples & full panels
$79 & up
Best value: single tests
$49 & up
Every kit uses CLIA-certified labs. At-home testing is for screening; a reactive result should be confirmed and treated by a clinician. Prices and panels shown are illustrative and change often, confirm current details on the provider's site.
Also in the area
Beyond the public testing sites above, these federally certified (CLIA) labs serve Jefferson County, each lab's town is shown on its card below. Many test through a doctor's order or by appointment rather than walk-in, so call ahead to confirm STD/STI testing and availability before visiting.
1011 Bowles Ave Suite G50, Fenton, MO 63026
CMS-certified lab Accredited · Joint Commission
1400 Highway 61 South, Festus, MO 63028
CMS-certified lab Accredited · College of American Pathologists
3783 Vogel Road, Arnold, MO 63010
CMS-certified lab
Source: CMS CLIA registry (Provider of Services), Q1 2026. Federal public records: active CLIA-certified laboratories near De Soto. A CLIA certificate records only that a laboratory is federally certified — it does not confirm the site performs STD testing, nor its hours, price or access. Inclusion is not an endorsement; always call to verify.
Local clinicians
Beyond dedicated clinics, 429 primary-care, OB-GYN, infectious-disease and other clinicians have a CMS practice record within 30 miles of De Soto. They may be able to evaluate symptoms or order a confidential STD panel during a regular visit, and 110 offer telehealth.
Ashutosh Patel, MD
Internal medicine · 106 Easton Street, De Soto
Mariela Del Valle Cruz
Family medicine · 1550 Villa Drive, De Soto
Pascal Gaudreault, MD Telehealth
Family medicine · 405 Main Street, Hillsboro
Fredric Melton, MD Telehealth
Family medicine · 5194 Jeremiah Boulevard, Hillsboro
Earl Draves, MD
Family medicine · 1471 US Hwy 61, Festus
Jeffrey Draves, MD
Family medicine · 1471 US Hwy 61, Festus
These are registry-listed clinicians, not dedicated STD-testing clinics. CMS records do not independently verify current licensure, testing services, availability, price, or new-patient status. Confirm each detail before booking. Source: CMS Doctors & Clinicians.
Nearby pharmacies
No pharmacy near De Soto, MO publishes an STD-related service or holds a current CLIA testing certificate, so these are simply the closest. Contact a location directly to confirm counter hours, services, prices, and availability before visiting.
De Soto Drug
0.4 miWestland Health Mart Pharmacy
0.8 miLin-Kris Pharmacy
0.9 mi
1.0 mi 
1.1 mi Showing the 5 closest pharmacies to De Soto, MO.
Directory records identify nearby pharmacies. Service, stock, price, and hours information is shown only when supported by current location-specific evidence.
Prevention & treatment
Testing is one step. For residents of De Soto, telehealth covers the rest: HIV-prevention medication (PrEP) and DoxyPEP to lower future risk, and discreet online treatment if a result comes back positive. All prescribed by licensed U.S. clinicians.
Visit from $39
Online STI treatment & DoxyPEP: same-day prescriptions to your pharmacy
$0 with most insurance
Free online PrEP & DoxyPEP: HIV prevention, home lab kits, no in-person visit
Visit from $0 insured
Telehealth STI treatment and sexual-health care, delivered or to your pharmacy
From $0 insured
Telehealth PrEP & DoxyPEP with at-home testing and ongoing monitoring
Pricing varies by insurance and changes often, confirm on the provider's site. These services are not a substitute for emergency care.
STD stats & rates
How reported STI rates in Jefferson County, the county that includes De Soto, compare with Missouri and U.S. averages, based on the most recent 2023 surveillance data. An estimated ~29% of residents are aged 15–34 (ACS), the age group with the highest reported chlamydia and gonorrhea rates nationally.
#55 of 115 Missouri counties for chlamydia, a higher rate than 52% of the state
| Infection | Jefferson County | Missouri | United States |
|---|---|---|---|
| Chlamydia | 237.9 550 cases ▼ 52% | 498.6 | 492.2 |
| Gonorrhea | 73.1 169 cases ▼ 64% | 201.9 | 179.5 |
| Syphilis (P&S) | 11.2 26 cases ▼ 48% | 21.5 | 15.8 |
| Syphilis (early) | 6.1 14 cases ▼ 51% | 12.4 | 16 |
| Syphilis (late/unknown) | 17.3 40 cases ▼ 49% | 33.8 | 29.5 |
Rates per 100,000 population, 2023. Source: CDC NCHHSTP AtlasPlus (county, state & U.S., all-ages basis). Population figures: U.S. Census Bureau ACS. These figures are the latest available surveillance estimates. Bars are scaled to the highest rate shown.
Reading these numbers: reported case rates only count infections that were actually tested for and diagnosed, so they track local screening effort as much as true spread: a higher rate can reflect more testing, a lower one less. Either way, most STIs cause no symptoms, so treat the figures above as context rather than a verdict, and test on the CDC's schedule regardless of how your area looks.
Between 2020 and 2023 in Jefferson County, chlamydia has risen from 218.3 to 237.9 per 100,000 (9%), gonorrhea has fallen from 94.4 to 73.1 per 100,000 (23%), and P&S syphilis has risen from 4.4 to 11.2 per 100,000 (155%).
The 2020 dip reflects reduced pandemic-era screening, not lower transmission. Source: CDC NCHHSTP AtlasPlus (county, state & U.S., all-ages basis).
Community health context
Sources: CDC PLACES (ZIP), County Health Rankings, CDC/ATSDR SVI, HRSA HPSA, HRSA MUA/P, Neighborhood Atlas ADI. Lower insurance coverage, fewer routine checkups, and a thin primary-care ratio all raise the value of low-cost public clinics and at-home testing in Jefferson County.
Local HIV snapshot
Federal priority area: Missouri is one of the U.S. jurisdictions prioritized under the Ending the HIV Epidemic initiative: targeted federal funding to expand local HIV testing, PrEP, and prevention.
Jefferson County HIV care continuum (2023)
Jefferson County recorded 3.1 new HIV diagnoses per 100,000 (2023), against 10.6 statewide and 13.7 nationally. Among Jefferson County residents living with HIV, 82.7% are in care · 73.3% are virally suppressed. Early, routine testing is what moves these numbers: it is the entry point to PrEP, treatment, and viral suppression.
Sources: AIDSVu (Emory/Gilead) · CDC AHEAD · CDC AtlasPlus · CDC NCHHSTP AtlasPlus (county care continuum). The CDC recommends everyone aged 13–64 test for HIV at least once: every lab and clinic listed above offers HIV testing, and free rapid HIV testing is available at a local health department.
Congenital syphilis, passed from parent to baby in pregnancy, is the fastest-rising STI in the country. U.S. cases climbed from 2,163 in 2020 to 3,882 in 2023. It is almost entirely preventable: the CDC recommends a syphilis test at the first prenatal visit, and every clinic and lab listed for Jefferson County tests for syphilis.
Source: CDC NCHHSTP AtlasPlus, 2023 (county-level congenital syphilis is not published).
Local resources & officials
Data & references
Local context
Along Donnelly Street and the side roads feeding into it, work rarely fits a tidy nine-to-five pattern: with a meaningful share of residents outside the labor force entirely and unemployment running higher than most nearby areas, the people who are working often piece together hours across shifts or multiple jobs, leaving almost no slack for clinic visits that require taking half a day off. That compressed reality falls hardest on younger adults still building careers and relationships, the years when STI rates climb sharpest and when a skipped appointment can go unnoticed for months. The housing picture adds another layer. Nearly four in ten households here rent, and at roughly $729 a month that sounds manageable until you factor in a household size averaging above three people.
Meaning most of that rent covers a family, not a single adult with flexible time. Tight budgets and full houses mean that low-cost or no-cost testing isn't just a convenience; for a lot of De Soto families it's the only version that actually works. The options listed on this page span a range of fees precisely because the gap between $0 and even a modest copay matters here. Narrow that list by hours and distance first, and the decision mostly makes itself.
Getting there
At 7.25/20 on the EPA walkability index, day-to-day errands in De Soto generally mean driving: plan on a car or rideshare to reach a clinic, and check each listing's hours and phone before you go.
Source: EPA National Walkability Index 2021.
ZIP 63020 snapshot
ZIP-level Census figures for the wider 63020 area around De Soto: a single ZIP can span several communities, so they describe the area, not De Soto alone.
De Soto sits in Jefferson County, ZIP 63020. Local context that shapes where residents test:
Local landmarks
Major routes
Nearby cities & towns
Just outside De Soto? These nearby communities have their own testing guides: clinics, at-home kits, and free screening close to home.
Reference
Everything to know before you test in Jefferson County: the CDC's screening guidelines, each infection's detection window, per-test reference prices, and your privacy rights under Missouri law. If you have symptoms right now, our confidential symptom checker maps them to the tests worth considering.
Based on current CDC screening recommendations.
| Group | Tests | How often |
|---|---|---|
| Everyone aged 13–64 | HIV | At least once |
| Sexually active women under 25 | Chlamydia, gonorrhea | Every year |
| Women 25+ with new or multiple partners | Chlamydia, gonorrhea | Every year |
| Pregnant people | HIV, syphilis, hepatitis B & C, chlamydia | Early in pregnancy |
| Gay & bisexual men (MSM) | Chlamydia, gonorrhea, syphilis, HIV | Every 3–6 months |
| Anyone who shares injection equipment | HIV, hepatitis B & C | At least yearly |
| All adults at least once | Hepatitis C | At least once |
Testing too early can return a false negative, confirm timing with a De Soto-area provider.
| Infection | Earliest reliable test | Sample |
|---|---|---|
| Chlamydia | 1–2 weeks | Urine or swab |
| Gonorrhea | 1–2 weeks | Urine or swab |
| Trichomoniasis | 1–4 weeks | Urine or swab |
| HIV (NAT / RNA) | 10–33 days | Blood |
| HIV (4th-gen Ag/Ab) | 18–45 days | Blood |
| HIV (antibody) | 3–12 weeks | Blood / oral |
| Syphilis | 3–6 weeks | Blood |
| Hepatitis B | 3–6 weeks | Blood |
| Hepatitis C | 8–11 weeks | Blood |
| Herpes (HSV) | 4–16 weeks (antibody); swab a sore | Blood / swab |
These are the federal Medicare reference prices for processing each lab test. Public clinics and the community health centers serving De Soto often test free or on a sliding scale; private labs and at-home kits bundle several tests into one fee. Use this as a per-test benchmark before you pay out of pocket, or see the full guide to STD test costs for insurance, free, and at-home options.
| Test | Reference price | CPT / HCPCS |
|---|---|---|
| Chlamydia (NAAT) | $47.80 | 87491 |
| Gonorrhea (NAAT) | $47.80 | 87591 |
| Trichomoniasis (NAAT) | $47.76 | 87661 |
| HIV-1/2 antigen/antibody | $26.87 | 87389 |
| HIV-1/2 antibody | $22.44 | 86703 |
| Syphilis (RPR/VDRL) | $5.61 | 86592 |
| Syphilis (treponemal antibody) | $17.49 | 86780 |
| Herpes (HSV NAAT) | $47.76 | 87529 |
| Hepatitis B surface antigen | $15.33 | 87340 |
| Hepatitis C antibody | $29.16 | 86803 |
Source: Medicare Clinical Laboratory Fee Schedule, CMS, 2025 rates (data.cms.gov). Reference rate for the lab assay only: a clinic visit, sample collection, or a bundled multi-test panel may cost more. Medicaid and most insurers cover STD screening at no out-of-pocket cost.
Two things that actually depend on Missouri law: who can consent, and whether partners can be treated without their own visit. Everything else about testing privately is the same nationwide (see below).
In Missouri, a minor of any age can consent to confidential STI testing and treatment on their own, no parental permission is required.
Missouri permits Expedited Partner Therapy (EPT): if you test positive for chlamydia or gonorrhea, your provider can give you medication (or a prescription) to pass to your partner, no separate exam or appointment needed for them.
Keeping a test private works the same in every state. Whether an STD test shows on insurance (the EOB), how to test anonymously, and self-pay options that leave no insurance trail don’t change by location.
Learn more about confidential STD testing in MissouriSource: Guttmacher Institute, Minors' Access to STI Services; CDC, Legal Status of Expedited Partner Therapy. General information, not legal advice.
Good to Know
Answers to the questions people ask most before getting tested.
Yes, several local labs offer same-day walk-in testing; best to call first.
Yes, Medicaid typically covers it, and public clinics are free either way.
Jefferson County Health Department, about 5.6 mi away, provides free testing.
A full panel typically covers chlamydia, gonorrhea, syphilis, HIV, and hepatitis B and C.
Jefferson County reported ~238 chlamydia cases per 100,000 in 2023, below the Missouri average.
At-home kits mail to 63020: self-collect, send to the lab, results in ~2–5 days.
In Missouri, people under 18 can consent to confidential STD testing and treatment on their own.
Untreated chlamydia can lead to pelvic inflammatory disease and fertility problems, caught early, it's cured with antibiotics.
Get treated, notify partners, pause sex until cleared, and follow up, the infection is manageable.
Often, yes, especially throat and rectal infections, which is why site-specific testing matters.
Have a different question? Browse the full STD & STI FAQ library, every question we answer, in one place.