Pregnancy safety
Is it safe during pregnancy?
Search 78 everyday medicines, foods, activities, and beauty products, each with one plain verdict — generally OK, caution, or avoid — and the ACOG, FDA, CDC, or MotherToBaby guidance behind it. It's general guidance, not a green light: your provider knows your situation. Searching runs on your device; nothing is sent or saved.
Every verdict traces to published ACOG, FDA, CDC, or MotherToBaby guidance — and anything with mixed evidence lands in caution, never OK.
General guidance only — your provider knows your situation. Never start or stop any medicine — prescription or over-the-counter — without them.
Search the pregnancy safety list
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Try a brand name too — "Tylenol", "Sudafed", "sushi", "hot tub", "retinol"…
Showing all 78 entries — general guidance only; your provider knows your situation.
Prescription medicines
No verdicts here — on purpose
Whether a prescription drug belongs in your pregnancy depends on your condition, your dose, and your alternatives — things no lookup table can know. One rule is universal: never stop or start a prescribed medicine without the prescriber who manages it. Abruptly stopping an antidepressant, seizure medicine, thyroid or blood-pressure drug can be far more dangerous than continuing it. For a free, confidential, expert answer about any specific medicine, contact MotherToBaby at 866-626-6847.
OTC medicines & supplements
Over-the-counter products only. Prescription medicines are deliberately not given verdicts here — see the note above the list.
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Acetaminophen (Tylenol)
Generally considered OKACOG considers acetaminophen a reasonable first choice for pain and fever at standard package doses — use the lowest dose that works, for the shortest time. Research into prenatal use is ongoing, so tell your provider you're using it.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Aspirin, low-dose (81 mg)
Caution — ask your provider firstOnly if your provider prescribed it: low-dose aspirin is recommended for some pregnancies to lower preeclampsia risk, but that's a provider decision based on your history — never a self-start.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Aspirin, regular strength
AvoidFull-dose aspirin is an NSAID and carries the FDA's avoid-at-20-weeks-and-later warning, plus bleeding concerns near delivery. The prescribed low-dose version (next entry) is a separate question.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Bismuth subsalicylate (Pepto-Bismol)
AvoidIt contains a salicylate — the same drug family as aspirin — so it carries NSAID-type concerns, especially in the second half of pregnancy. Ask your provider about alternatives instead.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Calcium-carbonate antacids (Tums)
Generally considered OKCalcium-based antacids are the standard first-line answer for pregnancy heartburn in ACOG patient guidance. Stick to package doses and mention frequent heartburn at your next visit.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Cetirizine (Zyrtec)
Generally considered OKLike loratadine, cetirizine is among the antihistamines ACOG describes as considered safe during pregnancy. Confirm daily use with your provider.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Dextromethorphan (cough suppressant)
Generally considered OKStudies to date haven't shown an increased risk of birth defects. Check the label for extra ingredients (alcohol, NSAIDs, decongestants) that change the answer, and confirm with your provider.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Diphenhydramine (Benadryl)
Generally considered OKAn older antihistamine with a long track record; studies haven't shown a pattern of birth defects. It's sedating, and it's still worth confirming with your provider before regular use.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Docusate (Colace)
Generally considered OKBarely absorbed and widely considered fine for pregnancy constipation, alongside fluids and fiber. Mention persistent constipation at a prenatal visit rather than escalating on your own.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Famotidine (Pepcid)
Generally considered OKAvailable studies haven't shown an increased risk, and it's commonly used when antacids aren't enough. Confirm the plan with your provider, especially for daily use.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Guaifenesin (Mucinex)
Caution — ask your provider firstEvidence on first-trimester use is limited, so most clinicians suggest holding off early in pregnancy. Ask your provider before using it at any stage.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Herbal supplements (general)
Caution — ask your provider firstHerbal products aren't FDA-reviewed for pregnancy safety, and 'natural' doesn't mean safe — some are known problems. Bring anything you take to your provider, or ask MotherToBaby about the specific herb.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
High-dose vitamin A (retinol) supplements
AvoidToo much preformed vitamin A (retinol) can cause birth defects. A standard prenatal vitamin uses safe forms and amounts — skip separate retinol or cod-liver-oil supplements unless your provider directs them.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Ibuprofen (Advil, Motrin)
AvoidAn NSAID. The FDA advises avoiding NSAIDs at 20 weeks of pregnancy and later because they can cause fetal kidney problems and low amniotic fluid. Earlier use only if your provider specifically okays it.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Isotretinoin (Accutane) — acne pills
AvoidIsotretinoin causes severe birth defects — the FDA requires the iPLEDGE safety program around it. If you take it and become pregnant, stop it immediately and call your prescriber right away — for isotretinoin specifically the FDA instruction is to stop the drug at once, not to keep taking it until you reach your prescriber.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Loratadine (Claritin)
Generally considered OKACOG lists newer antihistamines like loratadine among allergy medicines considered safe in pregnancy. Run your allergy plan by your provider anyway, especially if you take it daily.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Melatonin
Caution — ask your provider firstHuman pregnancy data are thin and supplement doses vary widely between brands. Talk sleep strategies through with your provider before reaching for it.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Naproxen (Aleve)
AvoidSame NSAID class and same FDA warning as ibuprofen: avoid at 20 weeks and later over fetal kidney and amniotic-fluid risks, and don't use earlier without your provider's okay.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Phenylephrine (oral decongestant)
Caution — ask your provider firstPregnancy data are limited and it can affect blood flow. Saline spray, humidified air, and rest are the safer first moves — ask your provider before taking it.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Prenatal vitamin with folic acid
Generally considered OKRecommended, not just allowed: the CDC advises 400 mcg of folic acid daily to sharply lower the risk of neural-tube defects, and a prenatal vitamin is the usual way to get it.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Pseudoephedrine (Sudafed)
Caution — ask your provider firstSome studies link first-trimester use to a small risk of abdominal-wall birth defects, and it can raise blood pressure. Most guidance says skip it in the first trimester and ask before using it after that.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them.
Foods & drinks
The short version: the real food risks in pregnancy are listeria, toxoplasmosis, mercury, and alcohol. Almost everything else is fine.
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Alcohol (any amount, any type)
AvoidThe CDC is unambiguous: there is no known safe amount, no safe type, and no safe time for alcohol in pregnancy. Fetal alcohol spectrum disorders are fully preventable by not drinking.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Artificial sweeteners (aspartame, sucralose, stevia)
Generally considered OKFDA-approved sweeteners are considered acceptable in moderation during pregnancy — the exception is aspartame if you have PKU. Water and milk are still the better defaults.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Caffeine under 200 mg a day
Generally considered OKACOG advises that moderate caffeine — under about 200 mg a day, roughly one 12-oz coffee — hasn't been linked to miscarriage or preterm birth. Count every source: tea, soda, energy products, chocolate.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Deli meats & hot dogs (served cold)
Caution — ask your provider firstCold cuts and hot dogs can carry listeria, which is far more dangerous in pregnancy. CDC guidance: heat them until steaming hot (165°F) just before eating, or skip them.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Energy drinks
Caution — ask your provider firstA single can can blow past the 200-mg caffeine line ACOG uses, and the added stimulant blends aren't tested in pregnancy. Ask your provider before using them at all.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Herbal teas
Caution — ask your provider firstHerbal teas aren't FDA-reviewed for pregnancy, and some herbs are concerning in quantity. An occasional cup of a common variety is likely fine — ask before making any of them a daily habit.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
High-mercury fish (shark, swordfish, king mackerel, tilefish, marlin, orange roughy, bigeye tuna)
AvoidThese are the FDA's 'choices to avoid' while pregnant: mercury accumulates and can harm a developing brain and nervous system.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Liver & liver products
Caution — ask your provider firstLiver is extremely high in preformed vitamin A, which can cause birth defects in large amounts. Occasional small portions at most — and ask your provider where your line is.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Low-mercury fish (salmon, shrimp, cod, tilapia, canned light tuna)
Generally considered OKFDA 'best choices' — 2 to 3 servings a week are actively encouraged for the omega-3s a developing brain needs. Cook seafood through while pregnant.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Premade deli salads (chicken, egg, tuna, seafood salad)
AvoidStore-counter salads are a named listeria risk for pregnancy in CDC guidance. Making the same salad fresh at home with cooked ingredients is fine.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Raw cookie dough & batter
AvoidIt's both the raw egg and the raw flour — flour can carry E. coli and isn't treated to kill it. Bake first; edible doughs made with treated flour and pasteurized egg are the workaround.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Raw fish & raw-fish sushi
AvoidRaw fish can carry parasites and bacteria that hit harder during pregnancy. Cooked rolls, veggie rolls, and fully cooked seafood are fine.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Raw or runny eggs
AvoidSkip raw and runny eggs — and homemade foods made with them — over salmonella risk, unless they're made with pasteurized eggs. Fully cooked eggs are fine.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Raw or undercooked meat & poultry
AvoidUndercooked meat is a classic route to toxoplasmosis and salmonella, both more serious in pregnancy. Use a food thermometer and cook meats to safe temperatures.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Raw sprouts (alfalfa, mung bean, clover)
AvoidBacteria can live inside the sprout seed itself, where washing can't reach — the FDA says cook sprouts thoroughly or skip them while pregnant.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Refrigerated pâté & meat spreads
AvoidRefrigerated pâtés and meat spreads are on the CDC's listeria list for pregnancy. Canned or shelf-stable versions are the safer swap.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Refrigerated smoked seafood (lox, nova)
Caution — ask your provider firstA listeria risk unless it's cooked into a hot dish or is the canned/shelf-stable kind, per FDA food-safety guidance. Ask, or save the bagel topping for after delivery.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Soft cheeses made from unpasteurized milk (queso fresco, some brie, feta, blue)
AvoidSoft cheeses made from raw milk are a leading listeria source in pregnancy per the CDC. The same cheeses made from pasteurized milk are considered OK — the label is the test.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Unpasteurized (raw) milk
AvoidRaw milk is a recognized listeria source the CDC tells pregnant people to avoid entirely. Pasteurized milk and dairy are fine — check the label.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Unpasteurized juice & cider
AvoidUntreated juice and cider can carry E. coli and other bacteria — the FDA says pregnant people should choose pasteurized versions. Nearly all shelf juice is pasteurized; farm-stand and fresh-squeezed often isn't.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Unwashed fruits & vegetables
AvoidProduce is great — just wash it first. Unwashed fruits and vegetables can carry toxoplasmosis and listeria from soil. Rinse well under running water and trim damaged spots.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them.
Activities & environment
Movement is encouraged in most pregnancies — the entries to watch are heat, falls, smoke, solvents, and a few infections.
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Applying pesticides & insect foggers
Caution — ask your provider firstDon't be the one applying them: have someone else do it, leave during application, and air the space out afterward. Ask your provider about anything beyond routine home use.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
CBD products
AvoidThe FDA specifically cautions against CBD during pregnancy — the fetal effects are unknown, and real-world products have contamination and undisclosed-THC problems.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Changing cat litter
Caution — ask your provider firstCat feces can carry toxoplasmosis. CDC advice: hand the litter box to someone else if you can; otherwise wear gloves, change it daily, and wash your hands well. No need to rehome the cat.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Contact & fall-risk sports (skiing, horseback riding, boxing, soccer)
AvoidACOG advises skipping activities with a high risk of falling or a blow to the abdomen during pregnancy. There are plenty of safer ways to stay active — see the exercise entry.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Diagnostic X-rays
Caution — ask your provider firstA single diagnostic X-ray is generally far below the radiation doses linked to harm, per ACOG — but always tell your provider and the technologist you're pregnant so they can shield, defer, or pick ultrasound/MRI instead.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Flying (commercial air travel)
Generally considered OKOccasional flying is generally considered OK up to about 36 weeks in an uncomplicated pregnancy per ACOG — airlines set their own cutoffs, so check yours. Move and hydrate on long flights, and ask first if you have complications.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Gardening in soil
Caution — ask your provider firstSame toxoplasmosis logic as the litter box — soil can carry it from outdoor cats. Wear gloves while you garden and wash your hands afterward.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Hot tubs & saunas
AvoidRaising your core temperature — especially in early pregnancy — is linked to neural-tube defects, so ACOG advises avoiding hot tubs and saunas. A warm (not hot) bath is fine.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Hot yoga & hot pilates
AvoidSame overheating concern as hot tubs: ACOG specifically advises against exercising in hot, humid conditions like heated studio classes. Regular prenatal yoga is a recommended alternative.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Household cleaning products
Generally considered OKTypical use with ventilation and gloves is considered fine. Never mix bleach and ammonia (dangerous for everyone), and leave industrial-strength products to someone else.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Insect repellent (DEET, picaridin)
Generally considered OKThe CDC says EPA-registered repellents, including DEET, are safe to use as directed in pregnancy — and worth using, because mosquito-borne infections are the real risk.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Marijuana / THC (smoked, vaped, or edibles)
AvoidThe FDA and CDC both advise against cannabis in any form during pregnancy: THC crosses the placenta and is linked to lower birth weight and developmental effects. That includes edibles — ask about alternatives for nausea or sleep.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Moderate exercise (walking, swimming, prenatal yoga)
Generally considered OKACOG recommends about 150 minutes of moderate activity a week in uncomplicated pregnancies — it helps, not harms. Confirm your plan at a prenatal visit, especially if you have any complications.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Paint strippers & solvent fumes
AvoidSolvents are among the exposures with real evidence of pregnancy harm at high levels. Let someone else do solvent-heavy work, and ventilate well if you're nearby.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Painting a room (latex/water-based)
Caution — ask your provider firstOccasional water-based painting with windows open is considered low-risk, but skip oil-based and spray paints — and never sand or strip old paint yourself. Ask about your specific project.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Sanding pre-1978 paint (lead)
AvoidSanding or scraping paint in homes built before 1978 can release lead dust, which harms a developing brain. This one is a hard delegate — stay out of the work area entirely.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Scuba diving
AvoidACOG says no: the fetus has no protection against decompression sickness. Surface snorkeling is the swap.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Secondhand smoke
AvoidSecondhand smoke exposure in pregnancy is linked to low birth weight and SIDS per the CDC. Make your home and car smoke-free, and ask the smokers in your life to take it outside — or quit with you.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Sex
Generally considered OKIn an uncomplicated pregnancy, sex is considered safe right up to delivery. Your provider will tell you if a specific condition — like placenta previa or preterm-labor risk — changes that.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Smoking (cigarettes)
AvoidSmoking raises the risk of preterm birth, low birth weight, certain birth defects, and SIDS per the CDC. Quitting at any point in pregnancy helps — free support exists at 1-800-QUIT-NOW.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Travel to Zika or malaria areas
AvoidThe CDC advises pregnant travelers not to visit areas with Zika risk and to weigh malaria zones very carefully — both infections can be devastating in pregnancy. Check CDC travel notices before booking.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Vaping & e-cigarettes
AvoidNot a safe alternative to smoking: the CDC notes nicotine itself damages a developing brain and lungs. Ask your provider about pregnancy-safe quit support instead of switching.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them.
Beauty & personal care
Most routines survive pregnancy intact. The consistent exceptions are vitamin-A-derived actives and a few high-absorption or unstudied treatments.
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Azelaic acid
Generally considered OKWidely considered one of the go-to pregnancy-compatible acne and rosacea ingredients. As with any routine, mention it at a prenatal visit.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Benzoyl peroxide
Generally considered OKOnly a small amount is absorbed, and it's a standard option for pregnancy acne in patient guidance. Confirm your overall acne routine with your provider or dermatologist.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Cosmetic Botox
Caution — ask your provider firstPregnancy data are scarce, so the standard advice is to defer cosmetic injections until after delivery. Medical uses of botulinum toxin are a decision for you and your prescriber.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Essential oils
Caution — ask your provider firstUnregulated, highly concentrated, and barely studied in pregnancy — and a few specific oils are flagged as problems. Occasional diluted or diffused use is probably low-risk, but ask before regular use.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Hair dye & highlights
Generally considered OKVery little dye is absorbed through the scalp, and guidance considers coloring OK — pick a ventilated space and gloves if you're doing it yourself (highlights touch the scalp even less). Many people still wait out the first trimester; ask if you're unsure.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Hydroquinone (skin lightener)
Caution — ask your provider firstStudies haven't shown a clear problem, but your skin absorbs an unusually large share of hydroquinone — so most guidance says hold off until after pregnancy. Ask about melasma-safe alternatives.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Nail polish & manicures
Generally considered OKOccasional manicures are considered fine — pick a well-ventilated salon. The studied concern is all-day occupational exposure for salon workers, not a customer's visit.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
New tattoos
Caution — ask your provider firstThe pregnancy-specific concerns are infection (hepatitis B and C, HIV) plus unstudied ink exposure — most guidance, and most artists, say wait. Talk to your provider if it can't.
Source: CDC General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Professional chemical peels
Caution — ask your provider firstMedium and deep peels push absorbed doses well beyond a face wash, and pregnancy data are limited. Defer, or clear the specific peel with your provider and dermatologist first.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Retinoid skincare (retinol, tretinoin, adapalene)
AvoidVitamin-A-derived actives are advised against in pregnancy: the oral form causes severe birth defects, so topicals are skipped as a precaution. Azelaic acid is a commonly suggested swap — ask your provider or dermatologist.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Salicylic-acid face wash (low strength)
Generally considered OKA rinse-off cleanser with a low percentage of salicylic acid is generally considered fine in pregnancy skin-care guidance. High-strength or leave-on versions are a different question — ask first.
Source: ACOG General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Self-tanner lotion
Generally considered OKDHA, the browning ingredient, barely penetrates the skin's outer layer, so lotions and mousses are considered fine. The spray-booth version is a separate entry.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Spray-tan booths
Caution — ask your provider firstThe concern is breathing in the mist, not the skin contact — inhaled DHA hasn't been studied in pregnancy. Use a lotion instead, or ask your provider.
Source: MotherToBaby General guidance only — your provider knows your situation. Never start or stop any medicine without them. -
Sunscreen
Generally considered OKRecommended, not just allowed: pregnancy skin is more prone to darkening (melasma), and sun protection helps. Mineral formulas (zinc oxide, titanium dioxide) are the pick if absorption worries you.
Source: FDA General guidance only — your provider knows your situation. Never start or stop any medicine without them.
Nothing here matches that search
We only list items where major-organization guidance is unambiguous — and prescription medicines never get verdicts here. For anything not on the list, MotherToBaby's free, confidential experts cover thousands of exposures: browse their fact sheets or call 866-626-6847. And your provider always knows your situation best.
Every verdict above is general guidance distilled from published ACOG, FDA, CDC, and MotherToBaby patient guidance — an estimate of where mainstream advice sits, not a diagnosis, a prescription, or a green light. Your provider knows your history, your medicines, and your pregnancy; the next step for anything you're unsure about is asking them. Never start or stop any medicine without them.
Already exposed?
If you already took, ate, or did something on this list
Don't panic, and don't sit with the guilt — a single exposure is rarely an emergency, and most "avoid" entries are about patterns and probabilities, not one deli sandwich or one glass of wine before you knew. The right move is information, not fear: call your provider, or reach MotherToBaby at 866-626-6847 (free, confidential, expert) to talk through the specific exposure.
Two situations skip the queue: for a suspected overdose or poisoning, call Poison Help at 1-800-222-1222, free and staffed 24/7. And for severe symptoms — trouble breathing, heavy bleeding, loss of consciousness — call 911 now.
How this list works
Where the verdicts come from
Every entry traces to published patient guidance from four sources: ACOG (the American College of Obstetricians and Gynecologists), the FDA, the CDC, and MotherToBaby (the nonprofit exposure-information service of teratology specialists). If those organizations don't give a clear answer about something, it isn't on this list — we'd rather send you to an expert than guess.
The three verdicts are deliberately blunt. "Generally considered OK" means mainstream guidance treats typical use as low-risk — it still isn't a personal green light, which is why every one says to loop in your provider. "Caution" means the evidence is limited or mixed, or the answer genuinely depends on trimester, dose, or your health — anything with mixed evidence lands here, never in OK. "Avoid" means major-organization guidance says skip it while pregnant; it's a statement about published guidance, never a judgment about you.
Just as important is what's deliberately missing: no doses beyond published thresholds, no drug-interaction logic, and no verdicts on prescription medicines — those answers belong to your prescriber and services like MotherToBaby, because they depend on your situation in ways a table can't capture.
Next steps
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Sources
Where this comes from
The verdicts distill ACOG patient FAQs on medications, food, exercise, and travel; the FDA's NSAID warning, fish/mercury advice, and sweetener rulings; CDC guidance on alcohol, listeria, toxoplasmosis, and tobacco; and MotherToBaby's exposure fact sheets. We summarize their positions — we don't invent our own.
Medically Reviewed & Fact-Checked · Updated
Reviewed by EasySTD Editorial Team
Compiled and checked by EasySTD's editorial team against CDC and public-health sources. This is educational information, not a substitute for advice from a licensed clinician. Our editorial guidelines →
5 Sources
Data & references
- FDA: Avoid NSAIDs at 20 weeks or later in pregnancy (Drug Safety Communication)https://www.fda.gov/drugs/drug-safety-and-availability/fda-recommends-avoiding-use-nsaids-pregnancy-20-weeks-or-later-because-they-can-result-low-amniotic
- FDA: Advice About Eating Fish (mercury list, best choices)https://www.fda.gov/food/consumers/advice-about-eating-fish
- CDC: Alcohol Use During Pregnancyhttps://www.cdc.gov/alcohol-pregnancy/about/index.html
- USDA MyPlate: Pregnancy & breastfeeding nutritionhttps://www.myplate.gov/life-stages/pregnancy-and-breastfeeding
- MotherToBaby: Fact sheets on exposures in pregnancyhttps://mothertobaby.org/fact-sheets/
EasySTD is an information and comparison directory, not a healthcare provider. This tool is general information based on published ACOG, FDA, CDC, and MotherToBaby guidance: it is not medical advice, a diagnosis, or a prescription, and it does not create a doctor-patient relationship. Your provider knows your situation — never start or stop any medicine without them.
Good to Know
Pregnancy safety: frequently asked questions
Tylenol vs ibuprofen, the food risks that actually matter, prescription medicines, caffeine, and how private this lookup is.
Can I take Tylenol (acetaminophen) while pregnant?
Acetaminophen is what ACOG points to as a reasonable first choice for pain and fever in pregnancy — at standard package doses, for the shortest time that works. Untreated high fever carries its own risks, so 'tough it out' isn't automatically the safer move. You may have seen headlines about prenatal acetaminophen research; that work is ongoing, and the practical takeaway from major organizations hasn't changed: use it thoughtfully, not casually, and tell your provider you're taking it — especially if you find yourself needing it often, which is itself worth a conversation.
Why are ibuprofen and other NSAIDs on the avoid list?
Because the FDA issued a specific warning about them: at 20 weeks of pregnancy and later, NSAIDs like ibuprofen, naproxen, and full-dose aspirin can impair fetal kidneys and cause low amniotic fluid — problems that can appear after even a couple of days of use. Earlier in pregnancy, NSAIDs are still not a self-serve option; use them only if your provider specifically okays it. The one deliberate exception is low-dose (81 mg) aspirin prescribed by a provider to reduce preeclampsia risk in certain pregnancies — that's a prescriber's call, never a self-start.
What are the food risks that actually matter?
Four things drive nearly all pregnancy food guidance. Listeria — the reason behind the deli-meat, unpasteurized-cheese, raw-milk, smoked-seafood, and deli-salad entries — is rare but far more dangerous in pregnancy. Toxoplasmosis rides on undercooked meat and unwashed produce. Mercury accumulates in a handful of large predator fish, which is why the FDA publishes an avoid list while encouraging 2-3 weekly servings of low-mercury fish. And alcohol has no known safe amount at any point, per the CDC. Get those four right and the rest of the menu mostly takes care of itself.
What about my prescription medicines?
This tool deliberately gives prescription drugs no verdicts, because the right answer depends on your condition, your dose, and your alternatives — a lookup table can't know any of that. What is universal: never stop or start a prescription because of something you read, including here. Abruptly stopping an antidepressant, seizure medicine, thyroid or blood-pressure drug can be far more dangerous to a pregnancy than continuing it. Bring every medicine to your prescriber, ideally before conceiving, and use MotherToBaby (866-626-6847) — a free, confidential service whose experts cover exactly these questions.
Is caffeine really OK during pregnancy?
In moderation, yes. ACOG's guidance is that less than about 200 mg of caffeine a day — roughly one 12-ounce cup of coffee — has not been linked to miscarriage or preterm birth. The catch is that caffeine hides: tea, soda, energy drinks, chocolate, and some cold medicines all count toward the same 200 mg, and energy drinks can blow through it in one can while adding stimulant blends nobody has tested in pregnancy. If you're a multiple-cups-a-day person, taper rather than quitting cold to dodge withdrawal headaches, and ask your provider where your line should be.
Is what I search here private — and is it medical advice?
Private, yes; medical advice, no. The whole list is built into the page, and searching or filtering it happens entirely in your browser — nothing you type is sent to a server, saved, or shared, and closing the tab erases everything. We treat reproductive health lookups as sensitive by default. And every verdict here is general guidance distilled from ACOG, FDA, CDC, and MotherToBaby publications — it can't account for your history, your medications, or your pregnancy. Your provider can, which is why every entry ends the same way: ask them.
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