Simpsonville residents living in South Carolina with new HIV diagnoses run about 25% higher than the US average. If you've had a recent risk or simply test on a regular schedule, you have options. With some clinics taking walk-ins for same-day testing, and labs and at-home kits letting you plan around your own time, check below for your testing needs.
Available testing centers
9 testing options are listed for Simpsonville, SC. The nearest, Quest Diagnostics, is about 8.5 miles away. Compare community and public clinics, private labs, and at-home kits below.
Listings tagged Community health center are federally funded health centers and rural clinics that treat everyone regardless of insurance or ability to pay: required to bill on a sliding fee scale and provide confidential care, and in many states minors may consent to their own STI testing. A Title X tag flags centers funded for confidential family-planning services; confirm current participation when you call.
Source: CMS FQHC & Rural Health Clinic enrollment files (data.cms.gov), refreshed quarterly. Title X status reflects the latest OPA grantee list.
South Carolina Department of Public Health in Greenville pairs testing for gonorrhea, chlamydia, syphilis, herpes, hepatitis B, hepatitis C, and HIV with same-visit treatment for bacterial infections, all on a sliding-scale fee, and every service is provided at no cost.
The sliding scale at South Carolina Department of Public Health in Greenville bottoms out at zero, not zero for a subset of services, but zero across the entire visit. Testing, treatment, vaccines, PrEP, DoxyPEP, and counseling all carry the same price: nothing.
Prevention prescribing at many clinics begins and ends with PrEP. South Carolina Department of Public Health in Greenville also dispenses PEP and DoxyPEP, the doxycycline-based post-exposure antibiotic that cuts bacterial STI acquisition, giving patients access to the full current prevention toolkit in one appointment.
Herpes testing alongside hepatitis B and hepatitis C antibody screening extends the panel well past the four-infection baseline. At South Carolina Department of Public Health in Greenville, that broader scope means a single appointment surfaces conditions that narrower panels routinely leave undetected.
Languages
English
Tests offered
Serves
Care services
Prevention services
Fees & payment
Listing verified Aug 2025 · Source: CDC NPIN
Prisma Health in Greenville accepts Medicaid and most insurance, with a standard fee structure, and tests for gonorrhea, chlamydia, syphilis, HIV, herpes, hepatitis A, B, and C, and TB. Appointments required, bacterial infections treated same visit.
Prisma Health prescribes both PrEP and PEP as sustained clinical services, meaning PrEP comes with the follow-up HIV testing and kidney-function monitoring the regimen requires, built into care at the same practice rather than coordinated elsewhere.
Gonorrhea, chlamydia, syphilis, and HIV are the floor at most STI clinics: herpes testing and a full hepatitis sweep covering A, B, and C are where many stop short. Prisma Health in Greenville tests for all of them, alongside TB, in a single appointment.
Languages
English
Tests offered
Serves
Care services
Prevention services
Fees & payment
Listing verified Sep 2025 · Source: CDC NPIN
ReGenesis Health Care-Phoenix Center in Greenville meets patients where they are (between providers, paying cash, or working without insurance) through its federally qualified standing that ties fees to income. Syphilis, gonorrhea, and chlamydia screening is available on a sliding-scale basis, no appointment needed.
Tests offered
Fees & payment
New Horizon Family Health Services in Greenville is a family practice where every service (HIV, syphilis, gonorrhea, chlamydia, hepatitis A, B, and C, herpes, and TB) runs on a sliding scale, with Medicaid and insurance accepted and HIV testing free; walk-ins welcome, and same-visit treatment for bacterial STIs.
All services at New Horizon carry no fee. That means PrEP, hepatitis treatment, HIV care, and the full diagnostic panel are available without a bill waiting at checkout. Keeping follow-through as straightforward as the first visit.
Interpretation services are available for non-English languages across all care at New Horizon: including medication adherence counseling, PrEP initiation, and HIV treatment. That access extends to the clinical conversation itself, not just intake paperwork.
New Horizon holds Ryan White funding, which means the clinic carries HIV care from initial testing straight through ongoing antiretroviral treatment. A standing capability that serves anyone without consistent HIV care coverage, including those paying out of pocket.
Languages
English, Interpretation Services Available for Non-English Languages
Tests offered
Serves
Care services
Prevention services
Fees & payment
Listing verified Sep 2025 · Source: CDC NPIN + HRSA
Unity Health on Main in Greenville earned its federal qualification by committing to serve patients regardless of ability to pay, sliding-scale fees make that concrete. Walk-ins are welcome for syphilis, gonorrhea, and chlamydia screening, whether someone is uninsured, between providers, or simply paying out of pocket.
Tests offered
Fees & payment
Free tool · not a clinic
Testing too soon can miss an infection. Enter the date of possible exposure to see the earliest a test can reliably detect each STI.
| Infection | Earliest reliable test | Conclusive after |
|---|---|---|
| Chlamydia | 7 days after exposure | 14 days after exposure |
| Gonorrhea | 7 days after exposure | 14 days after exposure |
| Trichomoniasis | 7 days after exposure | 28 days after exposure |
| HIV (NAT / RNA) | 10 days after exposure | 33 days after exposure |
| HIV (4th-gen Ag/Ab) | 18 days after exposure | 45 days after exposure |
| HIV (antibody) | 21 days after exposure | 84 days after exposure |
| Syphilis | 21 days after exposure | 42 days after exposure |
| Hepatitis B | 21 days after exposure | 42 days after exposure |
| Hepatitis C | 56 days after exposure | 77 days after exposure |
| Herpes (HSV) | 28 days after exposure | 112 days after exposure |
Guidance only, confirm timing with a clinician. A negative result before the conclusive date may need a repeat test.
Typical out-of-pocket ranges by option, actual cost depends on which tests you need.
Public / community clinic
Free HIV testing is common
Private lab (self-pay)
Never billed to insurance
At-home kit
Mailed to your door, private
Doctor / urgent care
Often $0 preventive with insurance
No centers match those filters. Clear the service-type filter or the opening-hours filters to see every center.
Every other option
Beyond the dedicated testing centers above: at-home kits by mail, hospital labs certified for STI testing, local clinicians who can order a panel during a regular visit, pharmacies for self-test kits and prescriptions, and online PrEP & treatment.
Test from home
The nearest testing center is about 9 miles away; if you'd rather skip the trip, an at-home kit ships to Simpsonville, you collect the sample privately, and mail it back to a CLIA-certified lab. Results come online in days, with a clinician available if anything is positive. Same labs as a clinic, no waiting room, and you can read how accurate at-home STD tests are before you order.
Want a free option first? The CDC-supported TakeMeHome (opens in a new tab) program mails free at-home HIV self-test kits, and, in many areas, free STI kits, to your door, with no insurance or payment needed. The paid kits below add broader panels and faster turnaround.
In-home collection
$79 & up
Best for simplicity & support
$89 & up
Best value: single tests
$49 & up
Every kit uses CLIA-certified labs. At-home testing is for screening; a reactive result should be confirmed and treated by a clinician. Prices and panels shown are illustrative and change often, confirm current details on the provider's site.
Also in the area
Beyond the public testing sites above, these federally certified (CLIA) labs serve Greenville County, each lab's town is shown on its card below. Many test through a doctor's order or by appointment rather than walk-in, so call ahead to confirm STD/STI testing and availability before visiting.
3970 Grandview Drive, Simpsonville, SC 29680
CMS-certified lab Accredited · College of American Pathologists
729 Southeast Main Street, Simpsonville, SC 29681
CMS-certified lab Accredited · College of American Pathologists
307 North Main Street, Simpsonville, SC 29681
CMS-certified lab Accredited · COLA
2801 Woodruff Road, Simpsonville, SC 29681
CMS-certified lab Accredited · COLA
211 Batesville Rd Suite A, Simpsonville, SC 29681
CMS-certified lab Accredited · COLA
Showing the nearest 5 CLIA-certified labs.
Source: CMS CLIA registry (Provider of Services), Q1 2026. Federal public records: active CLIA-certified laboratories near Simpsonville. A CLIA certificate records only that a laboratory is federally certified — it does not confirm the site performs STD testing, nor its hours, price or access. Inclusion is not an endorsement; always call to verify.
Local clinicians
Beyond dedicated clinics, 1,032 primary-care, OB-GYN, infectious-disease and other clinicians have a CMS practice record within 30 miles of Simpsonville. They may be able to evaluate symptoms or order a confidential STD panel during a regular visit, and 248 offer telehealth.
Amanda Okelly, MD Telehealth
Internal medicine · 727 Semain Street, Simpsonville
Edna Katherine Gettys, MD Telehealth
Internal medicine · 727 Semain Street, Simpsonville
Justin Holladay, MD
Internal medicine · 727 Semain Street, Simpsonville
Erik Baker, MD Telehealth
Internal medicine · 404 Southeast Main Street, Simpsonville
Leon Buffaloe Telehealth
Internal medicine · 114 B Hospital Drive, Simpsonville
Mark Purcell, DO Telehealth
Internal medicine · 110 B Hospital Drive, Simpsonville
These are registry-listed clinicians, not dedicated STD-testing clinics. CMS records do not independently verify current licensure, testing services, availability, price, or new-patient status. Confirm each detail before booking. Source: CMS Doctors & Clinicians.
Nearby pharmacies
No pharmacy near Simpsonville, SC publishes an STD-related service or holds a current CLIA testing certificate, so these are simply the closest. Contact a location directly to confirm counter hours, services, prices, and availability before visiting.
Charlie's Hometown Pharmacy
0.2 mi
0.3 mi Howards Pharamcy
0.6 miShowing the 3 closest pharmacies to Simpsonville, SC.
Directory records identify nearby pharmacies. Service, stock, price, and hours information is shown only when supported by current location-specific evidence.
Prevention & treatment
Testing is one step. For residents of Simpsonville, telehealth covers the rest: HIV-prevention medication (PrEP) and DoxyPEP to lower future risk, and discreet online treatment if a result comes back positive. All prescribed by licensed U.S. clinicians.
From $0 insured
Telehealth PrEP & DoxyPEP with at-home testing and ongoing monitoring
Visit from $39
Online STI treatment & DoxyPEP: same-day prescriptions to your pharmacy
Visit from $0 insured
Telehealth STI treatment and sexual-health care, delivered or to your pharmacy
$0 with most insurance
Free online PrEP & DoxyPEP: HIV prevention, home lab kits, no in-person visit
Pricing varies by insurance and changes often, confirm on the provider's site. These services are not a substitute for emergency care.
STD stats & rates
How reported STI rates in Greenville County, the county that includes Simpsonville, compare with South Carolina and U.S. averages, based on the most recent 2023 surveillance data. An estimated ~26% of residents are aged 15–34 (ACS), the age group with the highest reported chlamydia and gonorrhea rates nationally.
#29 of 46 South Carolina counties for chlamydia, a higher rate than 37% of the state
| Infection | Greenville County | South Carolina | United States |
|---|---|---|---|
| Chlamydia | 528.6 2,950 cases ▼ 14% | 612.1 | 492.2 |
| Gonorrhea | 185.8 1,037 cases ▼ 16% | 222.4 | 179.5 |
| Syphilis (P&S) | 15.2 85 cases ▼ 12% | 17.3 | 15.8 |
| Syphilis (early) | 26.7 149 cases ▲ 42% | 18.8 | 16 |
| Syphilis (late/unknown) | 1.3 7 cases ▼ 89% | 11.7 | 29.5 |
Rates per 100,000 population, 2023. Source: CDC NCHHSTP AtlasPlus (county, state & U.S., all-ages basis). Population figures: U.S. Census Bureau ACS. These figures are the latest available surveillance estimates. Bars are scaled to the highest rate shown.
Reading these numbers: reported case rates only count infections that were actually tested for and diagnosed, so they track local screening effort as much as true spread: a higher rate can reflect more testing, a lower one less. Either way, most STIs cause no symptoms, so treat the figures above as context rather than a verdict, and test on the CDC's schedule regardless of how your area looks.
Between 2020 and 2023 in Greenville County, chlamydia has fallen from 587 to 528.6 per 100,000 (10%), gonorrhea has fallen from 316.8 to 185.8 per 100,000 (41%), and P&S syphilis has fallen from 19.4 to 15.2 per 100,000 (22%).
The 2020 dip reflects reduced pandemic-era screening, not lower transmission. Source: CDC NCHHSTP AtlasPlus (county, state & U.S., all-ages basis).
Community health context
Sources: CDC PLACES (ZIP), County Health Rankings, CDC/ATSDR SVI, HRSA HPSA, HRSA MUA/P, Neighborhood Atlas ADI. Lower insurance coverage, fewer routine checkups, and a thin primary-care ratio all raise the value of low-cost public clinics and at-home testing in Greenville County.
Local HIV snapshot
Federal priority area: South Carolina is one of the U.S. jurisdictions prioritized under the Ending the HIV Epidemic initiative: targeted federal funding to expand local HIV testing, PrEP, and prevention.
Greenville County HIV care continuum (2023)
Greenville County recorded 17.1 new HIV diagnoses per 100,000 (2023), against 18.3 statewide and 13.7 nationally. Among Greenville County residents living with HIV, 83.7% are in care · 76.8% are virally suppressed. Early, routine testing is what moves these numbers: it is the entry point to PrEP, treatment, and viral suppression.
Sources: AIDSVu (Emory/Gilead) · CDC AHEAD · CDC AtlasPlus · CDC NCHHSTP AtlasPlus (county care continuum). The CDC recommends everyone aged 13–64 test for HIV at least once: every lab and clinic listed above offers HIV testing, and free rapid HIV testing is available at a local health department.
Congenital syphilis, passed from parent to baby in pregnancy, is the fastest-rising STI in the country. U.S. cases climbed from 2,163 in 2020 to 3,882 in 2023. It is almost entirely preventable: the CDC recommends a syphilis test at the first prenatal visit, and every clinic and lab listed for Greenville County tests for syphilis.
Source: CDC NCHHSTP AtlasPlus, 2023 (county-level congenital syphilis is not published).
Local resources & officials
Data & references
Local context
Southside Park sits near the center of a Simpsonville that runs harder than outsiders expect: nearly three in four residents own their homes, households here tend to be larger than average, and more than half of adults are married, which means schedules are built around more than one person's obligations. That kind of daily density, two working adults, school pickups, a commute down I-385 toward Greenville, makes finding a testing window feel like one more coordination problem rather than a simple errand. That coordination matters most for people in their late teens and twenties, a group that represents a meaningful slice of Simpsonville's population and the years when STI transmission is statistically most active.
The county STI figures visible elsewhere on this page reflect exactly that pattern. With roughly seven in ten residents participating in the workforce, the practical question is rarely whether someone intends to get screened but whether a clinic's hours actually align with a full-time schedule in a suburb where most errands require a car and a block of time. Someone heading out along Fairview Road or cutting off Northeast Main Street can check distance and same-week availability before committing the drive, rather than finding out at the door.
Getting there
At 6.46/20 on the EPA walkability index, day-to-day errands in Simpsonville generally mean driving: plan on a car or rideshare to reach a clinic, and check each listing's hours and phone before you go.
Source: EPA National Walkability Index 2021.
ZIP 29681 snapshot
ZIP-level Census figures for the wider 29681 area around Simpsonville: a single ZIP can span several communities, so they describe the area, not Simpsonville alone.
Simpsonville sits in Greenville County, ZIP 29681. Local context that shapes where residents test:
Local landmarks
Major routes
Nearby cities & towns
Just outside Simpsonville? These nearby communities have their own testing guides: clinics, at-home kits, and free screening close to home.
Reference
Everything to know before you test in Greenville County: the CDC's screening guidelines, each infection's detection window, per-test reference prices, and your privacy rights under South Carolina law. If you have symptoms right now, our confidential symptom checker maps them to the tests worth considering.
Based on current CDC screening recommendations.
| Group | Tests | How often |
|---|---|---|
| Everyone aged 13–64 | HIV | At least once |
| Sexually active women under 25 | Chlamydia, gonorrhea | Every year |
| Women 25+ with new or multiple partners | Chlamydia, gonorrhea | Every year |
| Pregnant people | HIV, syphilis, hepatitis B & C, chlamydia | Early in pregnancy |
| Gay & bisexual men (MSM) | Chlamydia, gonorrhea, syphilis, HIV | Every 3–6 months |
| Anyone who shares injection equipment | HIV, hepatitis B & C | At least yearly |
| All adults at least once | Hepatitis C | At least once |
Testing too early can return a false negative, confirm timing with a Simpsonville-area provider.
| Infection | Earliest reliable test | Sample |
|---|---|---|
| Chlamydia | 1–2 weeks | Urine or swab |
| Gonorrhea | 1–2 weeks | Urine or swab |
| Trichomoniasis | 1–4 weeks | Urine or swab |
| HIV (NAT / RNA) | 10–33 days | Blood |
| HIV (4th-gen Ag/Ab) | 18–45 days | Blood |
| HIV (antibody) | 3–12 weeks | Blood / oral |
| Syphilis | 3–6 weeks | Blood |
| Hepatitis B | 3–6 weeks | Blood |
| Hepatitis C | 8–11 weeks | Blood |
| Herpes (HSV) | 4–16 weeks (antibody); swab a sore | Blood / swab |
These are the federal Medicare reference prices for processing each lab test. Public clinics and the community health centers serving Simpsonville often test free or on a sliding scale; private labs and at-home kits bundle several tests into one fee. Use this as a per-test benchmark before you pay out of pocket, or see the full guide to STD test costs for insurance, free, and at-home options.
| Test | Reference price | CPT / HCPCS |
|---|---|---|
| Chlamydia (NAAT) | $47.80 | 87491 |
| Gonorrhea (NAAT) | $47.80 | 87591 |
| Trichomoniasis (NAAT) | $47.76 | 87661 |
| HIV-1/2 antigen/antibody | $26.87 | 87389 |
| HIV-1/2 antibody | $22.44 | 86703 |
| Syphilis (RPR/VDRL) | $5.61 | 86592 |
| Syphilis (treponemal antibody) | $17.49 | 86780 |
| Herpes (HSV NAAT) | $47.76 | 87529 |
| Hepatitis B surface antigen | $15.33 | 87340 |
| Hepatitis C antibody | $29.16 | 86803 |
Source: Medicare Clinical Laboratory Fee Schedule, CMS, 2025 rates (data.cms.gov). Reference rate for the lab assay only: a clinic visit, sample collection, or a bundled multi-test panel may cost more. Medicaid and most insurers cover STD screening at no out-of-pocket cost.
Two things that actually depend on South Carolina law: who can consent, and whether partners can be treated without their own visit. Everything else about testing privately is the same nationwide (see below).
In South Carolina, a minor of any age can consent to confidential STI testing and treatment on their own, no parental permission is required.
South Carolina permits Expedited Partner Therapy (EPT): if you test positive for chlamydia or gonorrhea, your provider can give you medication (or a prescription) to pass to your partner, no separate exam or appointment needed for them.
Keeping a test private works the same in every state. Whether an STD test shows on insurance (the EOB), how to test anonymously, and self-pay options that leave no insurance trail don’t change by location.
Learn more about confidential STD testing in South CarolinaSource: Guttmacher Institute, Minors' Access to STI Services; CDC, Legal Status of Expedited Partner Therapy. General information, not legal advice.
Good to Know
Answers to the questions people ask most before getting tested.
Quest Diagnostics, about 8.5 mi away, with 9 options within 30 miles.
Yes, Medicaid typically covers it, and public clinics are free either way.
Yes, free HIV testing is available at public clinics in the area.
A full panel typically covers chlamydia, gonorrhea, syphilis, HIV, and hepatitis B and C.
Greenville County reported ~529 chlamydia cases per 100,000 in 2023, below the South Carolina average.
In South Carolina, people under 18 can consent to confidential STD testing and treatment on their own.
Yes, PrEP, a daily pill that helps prevent HIV in HIV-negative people, is available in the area.
Reputable kits use the same lab methods as clinics; any positive should be confirmed and treated by a provider.
Chlamydia is checked with a simple urine sample or a swab; lab results usually come back in a day or two.
Usually urine or a swab for chlamydia/gonorrhea, and blood for HIV, syphilis, and hepatitis.
Have a different question? Browse the full STD & STI FAQ library, every question we answer, in one place.